Loss of p16inka4a confers susceptibility to metastatic melanoma in mice
Article Abstract:
Research on the susceptibility of mice to metastatic melanoma is examined in detail, with an assessment of a genetic factor which appears to be linked to this susceptibility.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2001
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Loss of p16Inka4a with retention of p19Arf predisposes mice to tumorigenesis
Article Abstract:
Research on the susceptibility of mice to tumors is examined in detail, with a focus on genetic predispositions arising from genetic research with mice.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2001
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p[15.super.Ink4b] is a critical tumour suppressor in the absence of p[16.super.Ink4b]
Article Abstract:
The article discusses on the p[15.super.Ink4b] that can fulfill a critical backup function for p[16.super.Ink4b] and provide an explanation for the frequent loss of the complete CDKN2b- CDKN2a locus in human tumours.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2007
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